What is the first action to take during a decompression?

During an in-flight decompression, the immediate priority is to protect oneself from the effects of reduced cabin pressure, which can lead to hypoxia (insufficient oxygen). Donning the nearest available oxygen mask is the first action because it ensures that the flight attendant quickly receives oxygen to maintain consciousness and function effectively in an emergency situation. This action is critical, as time is of the essence during decompression.

Once the mask is secured, the flight attendant can then proceed to assess cabin conditions, secure loose items, and notify the captain. These actions are also important but come after ensuring personal safety. The first step is all about immediate self-protection to be able to assist passengers and manage the situation effectively.